CREATINE

What is creatine?    Creatine monohydrate is a dietary supplement used for increasing muscle mass and improving performance in short-duration, high-intensity exercise.  It is popular with athletes, weight lifters, and body builders, and has been in use for the past 5 to 10 years.  The long-term risks of using creatine are not known.  Its use is not banned by the International Olympic Committee or other sports regulatory organizations.  Creatine is similar to an amino acid.  It is made naturally in your liver and then stored in your muscles.  In your diet it is found in red meat.  As a supplement it is usually sold in powder or tablet form.

How does it work?    When the muscles contract they use a substance called adenosine triphosphate (ATP), which is broken down into (ADP).  Creatine helps turn ADP back into ATP for the working muscles, giving them a greater energy source for short bursts of exercise such as sprinting.  Creatine has been shown to be especially effective in performance of repeated bursts of exercise because it enhances recovery.  Studies show that creatine increases the amount of water stored in muscles and increases muscle volume.  Almost all studies have been done in men. 

Most athletes taking creatine will gain between 2 and 10 pounds over 4 to 10 weeks.  Creatine makes athletes bigger but not more skillful or agile.  Between 20% and 30% of people don't benefit from creatine, and nobody knows why.  Athletes who compete in sports dependent on weight, power, and short bursts of intense activity (football, basketball) may benefit from creatine, while those in sports such as long-distance running may not.  Most studies have shown no improvement in swimming or cycling performance.

What are the side effects?    The side effects of short-term use are minimal.  Some people may develop an upset stomach or muscle cramping.  To avoid dehydration and possible muscle cramping, drink lots of fluids while you are taking creatine.  The risks of long-term use of creatine are not known, but some doctors believe that it could lead to kidney damage. 

The Sports Medicine Patient Advisor
by Pierre Rouzier, M.D.
Creatine p 287